![]() We observed a small-to-large effect size of MBIs for negative symptoms. We identified 26 randomized controlled trials including 1725 individuals with schizophrenia. Subgroup analysis and meta-regression analysis were used to explore the potential influencing factors of the pooled SMD of MBIs for negative symptoms. Standard mean differences (SMDs) with 95% confidence intervals (CIs) were calculated to assess effect sizes of MBIs for negative symptoms. We searched different databases and performed a meta-analysis to determine the efficacy of MBIs for the treatment of negative symptoms in schizophrenia. However, the effect size of MBIs and their potential influencing factors remain unclear. Mindfulness-based interventions (MBIs) can effectively relieve negative symptoms in patients with schizophrenia. ![]() ![]() Os efeitos da atividade física foram analisados para vários desfechos, entre os quais bem-estar, ansiedade, depressão, funções motoras e sociais foram avaliadas clinicamente ou por meio de relatos. As revisões apresentaram resultados de exercícios aeróbicos e anaeróbicos, práticas mente-corpo, esportes, entre outras, em populações sem transtornos mentais ou com transtornos mentais diversos (transtornos do neurodesenvolvimento e neurocognitivos transtornos depressivos transtornos de ansiedade espectro da esquizofrenia e outros transtornos psicóticos transtornos relacionados a substâncias e transtornos aditivos transtornos relacionados a trauma e a estressores transtornos alimentares diversos transtornos em saúde mental). Na avaliação da qualidade metodológica com a ferramenta AMSTAR 2, as RS foram consideradas de confiança criticamente baixa (97,1%) e de confiança baixa (2,9%). Resultados: De 2.891 registros identificados nas bases de dados, 71 RS foram incluídas após processo de seleção e elegibilidade. Os resultados foram reunidos em síntese narrativa conforme similaridade da população avaliada. Apenas o processo de seleção foi realizado em duplicata e de forma independente, a extração dos dados com posterior avaliação da qualidade das RS foi feita por um revisor e checada por outro. ![]() Foram utilizados atalhos de revisão rápida para simplificar o processo, com inclusão de RS publicadas nos últimos cinco anos e com algumas especificações quanto ao contexto e população. Métodos: Seguindo protocolo prévio, buscas por revisões sistemáticas (RS) foram realizadas em sete bases eletrônicas da literatura, em agosto de 2021. Pergunta: Quais são os efeitos da atividade física na saúde mental? However, the present findings justify further research on mind-body therapies for the treatment of negative symptoms. Overall, the currently available evidence remains limited and does not yet allow one to recommend mind-body therapies for the reduction of negative symptoms. Limitations in the available comparisons do not allow concluding on a specific effect of these interventions. Our results suggest a potential for meditation-based mind-body therapies in the treatment of negative symptoms, in particular for mindfulness-based approaches and to a lesser extent yoga. ![]() Our results did not show an increase of positive symptoms (N = 1051). A subgroup analysis for different types of therapy revealed a significant effect of mindfulness-based and yoga interventions on negative symptoms, but heterogeneity within the yoga subgroup was high. Overall, we found a beneficial effect of mind-body interventions on negative symptoms at endpoint compared to treatment-as-usual or non-specific control interventions, but the effect was small and moderate to high heterogeneity was present. The primary outcome was effect of mind-body therapies on negative symptoms and the secondary outcome was effect on positive symptoms.įifteen RCTs were included in the meta-analysis (N = 1081 patients). STEFAN KAISER MUSIC TRIALWe conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) examining effectiveness of yoga, tai-chi, qi-gong and mindfulness on negative symptoms of schizophrenia, using different databases and trial registries. Meditation-based mind-body therapies (yoga, tai-chi, qi-gong, mindfulness) have been suggested to have a potential therapeutic effect on negative symptoms. ![]()
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